A researcher at the Johns Hopkins Institute of Genetic Medicine has led the effort to compile to date the largest free resource of experimental information about human proteins. Reporting in the February issue of Nature Biotechnology, the research team describes how all researchers around the world can access this data and speed their own research.
Zounds, eh?
No anonymous postings. Only experimental results. (i.e. no predictions) You must be registered and logged-in to add data, but anyone can query.
Human Proteinpedia is a community portal for sharing and integration of human protein data. It allows research laboratories to contribute and maintain protein annotations. Human Protein Reference Database (HPRD) integrates data, that is deposited in Human Proteinpedia along with the existing literature curated information in the context of an individual protein. All the public data contributed to Human Proteinpedia can be queried, viewed and downloaded.
Data pertaining to post-translational modifications, protein-protein interactions, tissue expression, expression in cell lines, subcellular localization and enzyme substrate relationships can be submitted to Human Proteinpedia.
Protein annotations present in Human Proteinpedia are derived from a number of platforms such as
- Co-immunoprecipitation and mass spectrometry-based protein-protein interaction
- Co-immunoprecipitation and Western blotting based protein-protein interaction
- Fluorescence based experiments
- Immunohistochemistry
- Mass Spectrometric Analysis
- Protein and peptide microarray
- Western blotting
- Yeast two-hybrid based protein-protein interaction
And if you understood all that, this site's for you.
So far 71 labs have contributed information on 2,695 experiments covering 15,231 protein entries.
Zounds.
THIS IS WHAT THE WEB IS FOR.
The Web wasn't created just to distribute pron and LOLcats (although it's very good at that too).
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